Characterizing Multiscale Mechanical Properties of Brain Tissue Using Atomic Force Microscopy, Impact Indentation, and Rheometry

Micro-Mechanical Characterization of Lung Tissue Using Atomic Force Microscopy

Matrix stiffness strongly influences growth, differentiation and function of adherent cells. On the macro scale the stiffness of tissues and organs within the human body span several orders of magnitude. Much less is known about how stiffness varies spatially within tissues, and what the scope and spatial scale of stiffness changes are in disease processes that result in tissue remodeling. To b...

Mechanical properties of cancer cells depend on number of passages: Atomic force microscopy indentation study

Atomic Force Microscopy indentation of living cells

Atomic Force Microscopy (AFM) indentation on living cells in physiological medium is a well established technique used for investigation of the cell mechanical properties at nanoscale. However, interpretation of the experimental data obtained in such experiments is rarely a trivial task. This is happening because living cells have a complex response to the applied mechanical stress, response th...

characterizing the mechanical properties of rat brain tissue in tension

background: characterizing the mechanical properties of brain tissue is deemed important for developing a comprehensive knowledge of the mechanisms underlying brain diseases. mechanical properties of very soft tissues, such as brain until recently have been attracted the attention of researchers because these tissues do not tolerate mechanical loads. the mechanical properties of brain tissue, h...

Mechanical properties of brain tissue by indentation: interregional variation.

Although many studies on the mechanical properties of brain tissue exist, some controversy concerning the possible differences in mechanical properties of white and gray matter tissues remains. Indentation experiments are conducted on white and gray matter tissues of various regions of the cerebrum and on tissue from the thalamus and the midbrain to study interregional differences. An advantage...